Treatment Cycle 11 - Day 1

I'm getting my Perjeta as I write - 11 treatments down, 7 to go! Treatment has become so routine for me - it's funny to think back on my first treatment, when I packed my chemo bag as carefully as if I was going into battle. Now I hardly give it a second thought - we're in, we're out, and life goes on.


I got my favorite chair today, and it's crystal clear out, so the view is perfect (that's the ocean in the distance):


When I saw Dr. Hurvitz this morning, I asked her about a study that was published recently out of Sweden that found that increased coffee consumption is associated with significantly smaller invasive breast tumor sizes, a lower proportion of ER+ tumors, and improved disease-free survival among tamoxifen-treated women with ER+ breast cancer. Specifically, the study showed that caffeine (as well as caffeic acid) mimics the actions of antiestrogens and modifies major growth regulatory pathways, resulting in impaired cell-cycle progression and reduced cellular proliferation. 

Dr. Hurvitz hadn't seen the study, but I sent her the link and asked for her opinion. I only drink about three cups of coffee a week, but I could up my intake if she thought the study findings were legitimate. Fortunately, I love the taste of coffee, so it would be no hardship for me to drink more - but I'm really sensitive to the caffeine, so I would need to make sure to have it in the morning so that I could still sleep at night. It would make me feel good to be able to do something else (and something so easy) to try to  prevent recurrence.

Maddie and I talked about my period, which I haven't had since January. She said that between my Perjeta, Herceptin, and tamoxifen, it's not surprising that I would stop getting my period. However, if I go for a year without it, I will need to go to a gynecologist for an ultrasound of my uterus, and possibly get a biopsy of the uterine lining. This is because tamoxifen carries a higher risk of endometrial (uterine) cancer (approximately 2 out of 1000). Maddie assured me that there is no cause for concern, but it's just something to know could be out there.

~

Last week I saw Dr. Trott for my pre-op checkup, in preparation for my exchange procedure next Tuesday. Among other things, we selected my implants, which was a strange experience. Implants, it turns out, come in a dazzling variety of sizes and shapes. One determining factor in the selection is the size and shape of the "pocket" that has been created by the tissue expander. However, it's also a matter of taste, as with a cosmetic breast augmentation - how big you want to be, how natural you want to look. We selected what we thought would be the best one for me, but Dr. Trott will bring an array of different ones into the operating room. Bizarrely, she'll put them in and then the nurses sit me up, and then Dr. Trott will decide how they look and make a change if necessary. Thank God, I will be fully unconscious for all of that.

We also talked about fat grafting, which is the process of removing small amounts of fat from other parts of the body (in my case, the belly and thighs), processing it into a liquid, and reinserting it into the breast area. Because my chest is so thin (even before the mastectomy, I had a rather bony chest, and now it's really thin), fat grafting will help to soften the edges of the implants and make them less obviously fake. I don't have a whole lot of excess donor fat to use in the process, but Dr. Trott thought she could get enough. I told her that she's welcome to everything I've got!

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